In a recent study, vitamin B6 supplements have been shown to reduce depression and anxiety.
According to a recent study, taking high-dose vitamin B6 tablets can help with feelings of anxiety and depression.
Researchers from the University of Reading studied the effects of high doses of vitamin B6 on young adults and found that they felt less anxious and depressed after taking the supplements every day for a month.
The study, published in the journal Human Psychopharmacology: Clinical and Experimentaladds to the body of evidence supporting the use of supplements believed to alter brain activity levels for the prevention or treatment of mood disorders.
dr. David Field, the lead author of the study from the School of Psychology and Clinical Language Sciences at the University of Reading, said: “The functioning of the brain relies on a delicate balance between the excitatory neurons that carry information and the inhibitory neurons that act on it. prevent runaway activities.Recent theories have linked mood disorders and some other neuropsychiatric disorders to an imbalance in this balance, often toward increased brain activity.Vitamin B6 helps the body produce a specific chemical messenger that directs impulses in the brain inhibits, and our study links this calming effect to reduced anxiety in the participants.
While previous research has shown that multivitamins or marmite can lower stress levels, little research has been done on which vitamins are responsible for this impact.
Current research focuses on the possible role of vitamin B6, which is known to promote the body’s production of GABA (gamma-aminobutyric acid), a molecule that blocks nerve cell impulses in the brain.
In the current study, more than 300 people were randomly assigned to vitamin B6 or B12 supplements significantly higher than the recommended daily intake (about 50 times the recommended daily allowance) or a placebo. Participants took one a day with meals for a month.
The study showed that vitamin B12 had little effect compared to placebo during the trial period, but vitamin B6 made a statistically reliable difference.
Elevated levels of GABA in participants who took vitamin B6 supplements were confirmed by visual tests performed at the end of the trial, supporting the hypothesis that B6 was responsible for the reduction in anxiety. Subtle but harmless changes in visual performance were detected, consistent with controlled levels of brain activity.
dr. Field said: “Many foods, including tuna, chickpeas and many fruits and vegetables, contain vitamin B6. However, the high doses used in this trial suggest that supplements would be needed to have a positive effect on mood. It is important to recognize that this research is in an early stage and that the effect of vitamin B6 on anxiety in our study was quite small compared to what you would expect from medication.However, diet-based interventions have been much less troublesome. side effects than drugs, and so people may prefer them as an intervention in the future.”
He continues: “To make this a realistic choice, further research is needed to identify other diet-based interventions that benefit mental well-being, allowing different nutritional interventions to be combined in the future to give better results. A possible option would be to combine vitamin B6 supplements with talking therapies such as cognitive behavioral therapy to increase their effect.”
Reference: “High-dose Vitamin B6 Supplementation Reduces Anxiety and Enhances Visual Surround Suppression” by David T. Field, Rebekah O. Cracknell, Jessica R. Eastwood, Peter Scarfe, Claire M. Williams, Ying Zheng, and Teresa Tavassoli, July 19, 2022 , Human Psychopharmacology Clinical and Experimental.